Frontiers Journal of Neurology & Neuroscience

A Novel Non-invasive Approach For Measuring Upper Airway Collapsibility In Mice

Abstract

Introduction: Invasive procedures were previously developed for measuring pharyngeal collapsibility in rodents during expiration, when declining neuromuscular activity makes the airway unstable. We developed a non-invasive approach for streamlining collapsibility measurements by characterizing responses in physiologic markers of dynamic expiratory air?ow obstruction to negative nasal pressure challenges.

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