Background: India is a developing region with having a substantial young population. Coronary artery disease poses a great economic burden and puts a significant population at risk. The purpose of this study was to assess the burden of young ST-elevation MI (STEMI) patients, their clinical profile and Outcome.
Result: Young ST-elevation myocardial infarction comprised 9.4% (n=89) of the total of 943 patients of ST-elevation myocardial infarction. The mean age was 35.42 ± 4.55 years and 97.8% were male. 19.1% of the patients were very young (? 30 years). Smoking (46.1%) was the prevalent risk factor. Single vessel disease was present in 73.0% and the left anterior descending artery was the culprit in 72% of the patients.
In hospital mortality was 2.25%. In a mean follow-up of 51 ± 23 months (43 of 89), 16.3% of patients had a recurrence of angina. 9.3% presented with acute coronary syndrome, repeat intervention was done in 7% of patients. There was no further mortality. Only 77% reported a good quality of life.
Conclusion: STEMI in young Indians comprises a significant proportion of the total STEMI patients and is predominantly a disease of the male population. Smoking is the main risk factor and LAD is the most common culprit vessel involved. The short-term and long outcome is good but there is a significant recurrence of events on follow-up, repeat intervention is not uncommon and a significant proportion report less than optimal quality of life.